the DS will not phsycally connect to you PC. A GBAMP V2 or M2 simply put with Chism's firmware upgrade will run Homebrew. or a flash cart, supercard, M3, or whatever else you have that can me your DS run Homebrew apps http://www.dslinux.org/wiki/Running_Homebrew <-- the DSLinux Wiki gives a good definition for running homebrew once you run the app on the DS (DS2KEY) and set it up for the router, it will automaticly connect to the PC that is running the PC side app. just switch modes, then it will work